Organic Chemistry Laboratory - GMU
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http://mason.gmu.edu/~sslayden/Lab/318/318expts.htm Chemistry 318 Organic Chemistry Lab II Spring 2017 This syllabus can be found at http://mason.gmu.edu/~sslayden/Lab/index.html
Lab Text: D.L. Pavia, G.M. Lampman, G.S. Kriz, and R.G. Engel, Introduction to Organic Laboratory Techniques: A Small Scale Approach (GMU edition), 2011. Lab Manual: S.W. Slayden, R.J. Roth, and W.M. Stalick, Laboratory Manual Organic Chemistry 315,318, 2015. Lecture Text: T.W.G. Solomons, C.B. Fryhle, and S.A. Snyder, Organic Chemistry, 12th edition, 2016.
The procedures for most experiments are in the Lab Manual. If a procedure appears in both the Lab Text (Pavia) and the Lab Manual, the procedure in the Lab Manual will be used. Chem 314 lecture is a pre- or co-requisite for Chem 318 lab. You must obtain at least a C in Chem 313 and Chem 315 before you take Chem 318. If you previously took Chem 314, you must have at least a C in it to use it as a pre-requisite for Chem 318. If you drop or withdraw from Chem 314, you must also drop/withdraw from Chem 318. Add, drop, and selective withdrawal deadlines can be found at http://registrar.gmu.edu
Policies for Chemistry 318 (grading, safety, notebook format, etc.) appear in the Lab Manual on pages 1-21. These will be supplemented by your lab instructor. It is the responsibility of all students to be familiar with and adhere to the GMU Honor Code. Date
Experiment Title
Pages
Jan 23-27
Introduction and safety; check-in; NMR video
Lab Manual 1-21 Pavia 546-571, 575-578
Jan 30-Feb 3
Nuclear magnetic resonance spectroscopy (1H and 13C NMR); spectroscopy problem set
Lab Manual 77
pdf:
http://mason.gmu.edu/~sslayden/Lab/318/spectra-prob-set318-current.pdf
Pavia 886-888, 891-902, 904-914, 923-934 Solomons 391-419
doc:
http://mason.gmu.edu/~sslayden/Lab/318/spectra-prob-set318-current.doc
Feb 6-10
Bromination of toluene; review IR; NMR continued
Lab Manual 37-46, 79-88 Pavia 830-831, 852-854
Feb 13-17
Nitration of methyl benzoate
Lab Manual 89-92
Feb 20-24
Synthesis of 4,4’-di-tert-butylbiphenyl; nitration of methyl benzoate continued
pdf link
Feb 27-Mar 3
Identification of an unknown; GMU NMR Center
Lab Manual 97-98
Mar 6-10
Identification of an unknown continued
Mar 13-17
Spring break
Mar 20-24
Grignard synthesis of benzoic acid
Pavia 338-340, 671, 643
NMR Instructions (http://nmr.gmu.edu/318_1h.pdf) Pavia 723-725, 846-849
Lab Manual 99-102 Pavia 278-281, 286-288
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Organic Chemistry Laboratory - GMU
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http://mason.gmu.edu/~sslayden/Lab/318/318expts.htm
Mar 27-31
Isolation and recrystallization of benzoic acid
Lab Manual 99-102 Pavia 686-688, 693-694, 700-702
Apr 3-7
Qualitative & spectroscopic analysis of aldehydes and ketones
Lab Manual 103-105 Pavia 446-458, 468-474
Apr 10-14
Synthesis of banana oil
Pavia 84-91, 686-688, 693-697
Apr 17-21
Synthesis of dibenzalacetone
Lab Manual 111-112
Apr 24-28
Synthesis of biodiesel
Lab Manual 107-109
May 1-5
Lab check-out and final exam
Pavia 207-216
If you are a student with a disability and you need academic accommodations, please contact Disability Services at 993-2474, http://ds.gmu.edu. All academic accommodations must be arranged through Disability Services.
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