ORCA program Palermo - Unipa

May 7th Time

Program

16.00Registration 17.45 17.45Welcome and Opening remarks 18.00 Chair: Prof. Herbert Mayr 18.00- Plenary PL1 18.45 Carbene Catalysis Made Visible: Characterization of Intermediates by NMR and XRay Crystallography 18.50- Plenary PL2 19.35 Organocatalyzed Reductive Amination with Trichlorosilane 19.40- Oral O1 19.55 Enantioselective Halogenation-Initiated Semi-Pinacol Rearrangements 20.0020.15 20.3022.00

Oral O2 Synthesis and Desymmetrization of Prochiral Bicyclo[2.2.2]octene Derivatives Dinner

Speaker

Albrecht Berkessel Pavel Kočovský Fedor Romanov Michailidis Marko Krivec

May 8th Time

Program

Chair: Prof. Claudio Trombini 9.00Plenary PL3 9.45 Design of New Organoradical Catalysts for Selective C-H Activation and Asymmetric Cyclization 9.50Invited I1 10.20 Unexpected Activation of Reactivity of Isatin Derivatives 10.25- Oral O3 10.40 Synthesis of Activated Dienes: Attractive Substrates in Asymmetric Organocatalysis 10.45Coffee-Break - poster session 11.30 Chair: Prof. Alexandre Alexakis 11.30- Oral O4 11.45 Applying Vinylogous Reactivity in Aminocatalytic Cycloadditions 11.50- Oral O5 12.05 Dual Iron/Organo-Catalysis for Sustainable Enantioselective Synthesis 12.10- Oral O6 12.25 Direct, Organocatalytic, Enantioseletcive Michael Reactions: Turning Common Michael Acceptors Into Vinylogous Carbon Nucleophiles 12.30- Invited I2 13.00 Organocascade Reactions and Synergistic Catalysis: two open gates for the development of complex structures 13.10Time for Lunch and relax 15.00 Chair: Prof. Armando Cordova 15.00- Plenary PL4 15.45 Combined Experimental/Computational Mechanistic Studies of Organocatalytic Transformations 15.50- Oral O7

Speaker Keiji Maruoka Tonis Kanger John Stephens

Jose L.Vicario Adrien Quintard Claudio Curti Ramon Rios

Imre Papai Roman

16.05

Organocatalyzed Direct Vinylogous Double Michael Addition of Unactivated αAngelica Lactone to Enones Oral O8 Mukaiyama–Michael Reactions with Trans-2,5-Diarylpyrrolidine Catalysts Time for discussion-poster

16.1016.25 16.3017.30 Chair: Prof. Alessandra Lattanzi 17.30- Invited I3 18.00 Design of Experiment (DoE) in Non-Covalent Asymmetric Catalyzed Reactions 18.05- Oral O9 18.20 A Diagonal Approach to the Recycling of CO2 Using Organocatalysts 18.25- Oral O10 18.40 Water-Compatible Hydrogen-Bond Activation: A Scalable and Organocatalytic Model for the Stereoselective Multicomponent Aza-Henry Reaction 18.45- Invited I4 19.15 Amino Acids and their Derivatives as Catalysts for Organocatalytic Cascade Transformations 19.20Relax 20.00 20.00Dinner 22.00

Lagoutte Antti Piisola

Marco Bella Thibault Cantat Fernando GarcíaTellado Christoforos Kokotos

May 9th Time

Program

Chair: Prof. Petri Pihko 9.00Plenary PL5 9.45 Stereoselective Halocyclization Catalyzed by Chiral Lewis Bases 9.55Invited I5 10.25 Stereoselective Catalytic Synthesis of Chiral Trifluoromethyl Aryl and Alkyl Amines 10.30- Invited I6 11.00 Catalytic Asymmetric Crotylation: Method Development and Application in Total Synthesis 11.00Coffee-Break – poster 11.45 Chair: Prof. Angela Marinetti 11.45- Oral O11 12.00 Novel Thiazolium Based Heterogeneous Organocatalysts for Etherification Reactions 12.05- Oral O12 12.20 NHC-Catalyzed (hetero-)Michael Additions with NHC•CO2 Precatalysts

12.25- Invited I7 12.55 Enantioselective Organocatalytic Cycloadditions via Hydrogen Bond Catalysis 13.00Time for Lunch and relax 14.30 Chair: Prof. George Kokotos 14.30- Plenary PL6 15.15 Enantioselective Synthesis of Natural and Biologically Active 1,2,3,4Tetrahydroisoquinolines via Organocatalytic Pictet–Spengler Reactions 15.20- Invited I8 15.50 The Quest for Organoautocatalytic Reactions

Speaker Kazuaki Ishihara Maurizio Benaglia Andrei Malkov

Carmela Aprile Yoann Coquerel, Lionel Delaude Geraldine Masson

Jan Van Maarseveen Albert Moyano

16.0020.00 20.0022.00

Excursion Dinner

May 10th Time

Program

Chair: Gabriela Guillena 9.00Plenary PL7 9.45 Stereocontrol in Organic Synthesis: From Chiral Lewis Acid Catalysis to Organocatalysis 9.50Oral O13 10.05 (Thio)Urea Derivatives as Brønsted-Acid Organocatalysts 10.10- Oral O14 10.25 Quantifying the Nucleophilicity of Chiral Boron-Ate Complexes 10.30- Closing remarks 11.00 11.00Coffee break 11.20 11.20- MC meeting 12.30 13.00Lunch 15.00

Speaker Claudio Palomo Ádám Madarász Kathryn Feeney

Posters

Presenter

PO1

The Role of Noncovalent Interactions in Iminium Catalysis

PO2

Kinetic Resolution of Oxazinones: Rational Exploration of Chemical Space via Design of Experiments Novel Supported Ureas and Thioureas as Recoverable Catalysts for Enantioselective Transformations En Route to Multicatalysis: Kinetic Resolution of trans-cycloalkane-1,2-diols via Oxidative Esterification Organocatalytic Alcohol Oxidation Catalyzed by Recyclable TEMPO-functionalized [60]fullerene C60-TEMPO-IL hybrid: “release and catch” organocatalyst for the oxidation of alcohols Recyclable Chiral Imidazolidinone Catalyst for α-Alkylation of Aldehydes

Andrea Hamza Polyssena Renzi Rafael Pedrosa Christine Hofmann Hazi Ahmad Beejapur Vincenzo Campisciano Anna M.P. Salvo Gabriela Guillena Vincent Levacher Elisabetta Massolo Sergei Žari Anastassia Matviitsuk Maksim Ošeka

PO3 PO4 PO5 PO6 PO7 PO8

Enantioselective Addition of Ketones to Isatines using Binam-Prolinamides as Organocatalysts under Solvent-Free Conditions PO9 Organocatalyzed Enantioselective Protonation: Deracemization and Decarboxylative Protonation Processes PO10 An Organocatalytic Strategy for Stereoselective Additions of a Glyoxylate Anion Equivalent PO11 Remote Activation of Isatin for Efficient Asymmetric aza-Michael Reactions PO12 Organocatalytic Knoevenagel Reaction with 1,3-Dicarbonyl Compounds PO13 Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole

PO14 A New Simple Method for the pKa Evaluation of Brønsted Acids PO15 Metal-Free Synthesis of 1,2-Diols and Their Rearrangement to 2(5H)-Furanones

PO16 Strategies for the Synthesis of Phosphonates

PO17 Organocatalytic Domino Michael/Aldol Reaction of 3 Halogeno-1,2-Diones to α,βUnsaturated Aldehydes PO18 Enantioselective Access to γ-Butyrolactones Via Tandem HydroxymethylationLactonization Sequence PO19 Densely Substituted Pyrrolidine Amine-Based Catalysts for the Conjugate Addition Reaction PO20 Total Synthesis of Capsaicin Analogues from Lignin Derived Compounds by Combined Heterogeneous Metal, Organocatalytic and Enzymatic Cascade in One Pot PO21 Synthesis of 2-Deoxygalactosides through Multicatalysis

Manuel Orlandi Cristiana Margarita, Mauro Moliterno Ana Maria Faísca Phillips Alice Lefranc Sara Meninno Andrea Ruiz-Olalla Samson Afewerki Raffael C. Wende